Difference Between Lock And Key Model And Induced Fit Model Of Enzyme Action

Instead the substrate interacts with the active site and both change their shape to fit together.

Difference between lock and key model and induced fit model of enzyme action.

Two main theories are used to explain how enzyme substrate complexes form. According to this hypothesis the active site does not have a rigid lock and key conformation. The key difference between induced fit and lock and key is that in induced fit theory the binding of the substrate with the active site of the enzyme induces the modification of the shape of the active site into the complementary shape of the substrate. Similarities between induced fit and lock and key model.

The lock and key model and the induced fit hypothesis are two potential models for how substrates may bind in the active site of an enzyme. In this model though the key and the enzyme active site do not fit perfectly together. Enzymes have very precise shape which includes a cleft or pocket called active sites. There is no change in shape of the active site.

They are lock and key theory and induced fit theory. The induced fit model is an elaboration on the basic idea of the lock and key model. In this theory the substrate fits into an active site like a key into a lock. They are important in describing how enzymes increase the rate of a biological reaction through catalysis.

Induced fit and lock and key are the two models which describe the mechanism of action of the enzyme. The way a key the substrate fits into a lock the enzyme. Daniel e koshland formulated this hypothesis in 1959. The lock and key model suggests that the substrate is completely complementary in shape to the active site so that it fits in perfectly i e.